Isolated Human Primordial Follicles
Isolated Human Primordial Follicles

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Isolated Human Primordial Follicles
Isolated Human Primordial Follicles

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Development of the artificial ovary

Ovarian tissue transplantation is another alternative to in vitro follicle culture for fertility preservation, yet it bears the risk of re-introduction of cancer cells and suffers from inconsistent graft longevity. We aim to engineer an artificial ovary from individually isolated human follicles through creative matrix design, incorporating supportive cells, ECM and other biological cues to ensure successful tissue remodeling after transplantation.