Publications

Research from the Shikanov, Shea, and Domb Labs as well as talks given by Dr. Shikanov.

 

Publications from the Shikanov Lab

2021

67. Capitalizing on transcriptome profiling to optimize and identify targets for promoting early murine folliculogenesis in vitro 

Jones A, Peñalver Bernabé B, Padmanabhan V, Li J, Shikanov A.
Scientific Reports volume 11, Article number: 12517 (2021)

https://www.nature.com/articles/s41598-021-92036-y

66. A View from the past into our collective future: the oncofertility consortium vision statement 

Woodruff TK, et.al. 
Journal of Assisted Reproduction and Genetics, volume 38, pages3–15 (2021)

https://link.springer.com/article/10.1007/s10815-020-01983-4

 

65.  TNFRSF13B genotypes control immune-mediated pathology by regulating the functions of innate B cells 

Barbosa MGM, Lefferts AR, Huynh D, Liu H, Zhang Y, Fu B, Barnes J, Samaniego M, Bram RJ, Geha R, Shikanov A, Prak ETL, Farkash EA, JPlatt JL, Cascalho M.

JCI Insight. 2021. 

https://doi.org/10.1172/jci.insight.150483.

 

64. Swellable catheters based on a dynamic expanding inner diameter

Tennankore R, Brunette M, Cox T, Vazquez R, Shikanov A, Burns ML, Love B.
Journal of Materials Science: Materials in Medicine volume 32, Article number: 51 (2021)

https://link.springer.com/article/10.1007/s10856-021-06524-8

 

63. Fresh and cryopreserved ovarian tissue from deceased young donors yields viable follicle

Fan Y, Flanagan CL, Brunette MA, Jones AS, Baker BM, Silber SJ, Shikanov A.

F&S Science, 2021

https://doi.org/10.1016/j.xfss.2021.06.003

62. Sequestered cell-secreted extracellular matrix proteins improve murine folliculogenesis and oocyte maturation for fertility preservation, 

Tomaszewski CE, DiLillo KM, Baker BM, Arnold KB, Shikanov A.

Acta Biomaterialia, 2021

https://authors.elsevier.com/a/1cq%7EY6CFjZIakw

61. Reversibility of Testosterone Induced Acyclicity after Testosterone Cessation in a Transgender Mouse Model,

Kinnear HM, Hashim PH, Dela Cruz C, Rubenstein G, Chang FL, Nimmagadda L, Brunette MA, Padmanabhan V, Shikanov A, Moravek MB.

F&S Science, 2021

https://doi.org/10.1016/j.xfss.2021.01.008

2020

60. Impact of Exogenous Testosterone on Reproduction in Transgender Men, 

Moravek MB, Kinnear HM, George J, Batchelor J,  Shikanov A,  Padmanabhan V,  Randolph JF.

Endocrinology, Volume 161, Issue 3, March 2020

https://doi.org/10.1210/endocr/bqaa014

59. Hormonal Stimulation of Human Ovarian Xenografts in Mice: Studying Folliculogenesis, Activation, and Oocyte Maturation

Wall, MA, Padmanabhan V, Shikanov, A. 

Endocrinology, Volume 161, Issue 12, December 2020,

https://academic.oup.com/endo/article/doi/10.1210/endocr/bqaa194/5939202?guestAccessKey=390c169a-c4c9-46a4-97c5-1bf340e26c0f

      * This article has been selected as the Endocrinology Featured Article to be featured at the very top of the Endocrinology homepage @EndoSocJournals

58. Fiber Crimp Confers Matrix Mechanical Nonlinearity, Regulates Endothelial Cell Mechanosensing, and Promotes Microvascular Network Formation.

Davidson CD, Jayco DKP, Wang, WY, Shikanov A, Baker, BM .

J Biomech Eng., Nov 2020, 142(11), 

https://doi.org/10.1115/1.4048191

57. Ovarian Tissue Cryopreservation and Novel Bioengineering Approaches for Fertility Preservation. 

Jones ASK, Shikanov A.

Current Breast Cancer Reports 2020; 

https://doi.org/10.1007/s12609-020-00390-z

56. The ovarian stroma as a new frontier

Kinnear HM, Tomaszewski CE, Chang FL, Moravek MB, Xu M, Padmanabhan V, Shikanov A. 

Reproduction 2020; 160 (3)

   * This article was highlighted by the Editorial Board at the top 10 most viewed articles published this past year @ReprodJournal

https://doi.org/10.1530/REP-19-0501

55. Activation of goat primordial follicles in vitro: Influence of alginate and ovarian tissue

Correia HHV, Lima LF, Sousa FGC, Ferreira ACA, Cadenas J, Paes VM, Alves BG, Shikanov A, Figueiredo JR.  

Reprod Domest Anim. 2020 Jan;55(1):105-109.

Epub 2019 Nov 27. PMID: 31661715

https://www.ncbi.nlm.nih.gov/pubmed/31661715

2019

54. Immuno-Isolating Dual Poly (ethylene glycol) Capsule Prevents Cancer Cells from Spreading Following Mouse Ovarian Tissue Auto-Transplantation. 

Day JR, David A, Long C, Bushnell GG, Woodruff TK, Shea LD, Shikanov A. 

Regenerative Medicine Frontiers, 2019.

https://pdfs.semanticscholar.org/64f9/6fcd14526261efb3159d3a212874f6d68230.pdf

53. Encapsulation of ovarian allograft precludes immune rejection and promotes restoration of endocrine function in immune-competent ovariectomized mice. 

Day JR, David A, Barbosa MGM, Brunette MA, Cascalho M, Shikanov A.

Sci Rep. 2019 Nov 12;9(1)

https://www.ncbi.nlm.nih.gov/pubmed/31719632

52. A mouse model to investigate the impact of testosterone therapy on reproduction in transgender men

Kinnear HM, Constance ES, David A, Marsh EE, Padmanabhan V, Shikanov A, Moravek MB.

Hum Reprod. 2019 Oct 2;34(10)

​https://www.ncbi.nlm.nih.gov/pubmed/31585007

51. Adipose-derived stem cell-secreted  promote survival, growth and maturation of early-stage murine follicles,

Green LJ, Zhou H, Padmanabhan V, Shikanov A.  

Stem Cell Research & Therapy, 2019. 

https://doi.org/10.1186/s13287-019-1199-8

50. Adipose-derived stem cell-secreted factors promote early stage follicle development in a biomimetic matrix

Tomaszewski CE, Constance E, Lemke MM, Zhou H, Padmanabhan V, Arnold KB, Shikanov A.

Biomaterials Science, 2019

49. Follicle development as an orchestrated signaling network in a 3D organoid

 Jones ASK,  Shikanov A.

Journal of Biological Engineering, 2019, 13:2. 

https://doi.org/10.1186/s13036-018-0134-3

2018

48. Rapid Mouse Follicle Stimulating Hormone Quantification and Estrus Cycle Analysis Using an Automated Microfluidic Chemiluminescent ELISA System,

Tan X, David A, Day J, Tang H, Dixon ER, Zhu H, Chen Y, Kyaw M, Oo K, Shikanov A, Fan X.  

ACS Sensors, October 2018.

47. Synergy of Paracrine Signaling During Early-Stage Mouse Ovarian Follicle Development In Vitro.

Zhou H, Decker JT, Lemke MM, Tomaszewski CE, Shea LD, Arnold KB,  Shikanov A.

Cellular and Molecular Bioengineering, October 2018.

46. Secondary lymphoid organ fibroblastic reticular cells mediate trans-infection of HIV-1 via CD44-hyaluronan interactions.

Murakami T, Kim J, Li Y, Green GE, Shikanov A, Ono A.

Nature Communications. 2018

45. Three-dimensional Hydrogel-Based Culture to Study the Effects of Toxicants on Ovarian Follicles.

Zhou H, Shikanov A.

Methods Mol Biol. 2018;1758:55-7244. 

44. Synthetic PEG Hydrogel for Engineering the Environment of Ovarian Follicles.

Mendez U, Zhou H, Shikanov A.

Methods Mol Biol. 2018;1758:115-128.

43. Retrievable hydrogels for ovarian follicle transplantation and oocyte collection.

Rios PD, Kniazeva E, Lee HC, Xiao S, Oakes RS, Saito E, Jeruss JS, Shikanov A, Woodruff TK, Shea LD.

Biotechnol Bioeng. 2018 Apr 28. doi: 10.1002/bit.26721. 

42. Detection of lindane and 7,12-dimethylbenz[a]antracene toxicity at low concentrations in a three-dimensional ovarian follicle culture system,

Zhou H, Young CJ, Loch-Caruso R, Shikanov A. 

Reproductive toxicology, 2018

https://authors.elsevier.com/c/1Wyeu3AWI4GbBt

41. Immunoisolating poly(ethylene glycol) based capsules support ovarian tissue survival to restore endocrine function.

Day JR, David A, Cichon AL, Kulkarni T, Cascalho, M, Shikanov A. 

J. Biomed. Mater. Res., January 2018.

https://onlinelibrary.wiley.com/doi/abs/10.1002/jbm.a.36338

2017

40. The impact of functional groups of poly(ethylene glycol) macromers on the physical properties of photo-polymerized hydrogels and the local inflammatory response in the host, Day JR, David A, Kim J, Farkash EA, Cascalho M, Milasinovic N, Shikanov A.

Acta Biomaterialia, 2017. 

https://www.ncbi.nlm.nih.gov/pubmed/29242160

39. Fertility Preservation in 2016: Where Are We? 

David A, Green LJ, Shikanov A.

Seminars in Reproductive Medicine, Vol.35, No. 2/2017, pp. 160-166.

38. Restoring Ovarian Endocrine function with Encapsulated Ovarian Allograft in Immune Competent Mice.

David A, Day JR, Cichon AL, Lefferts A, Cascalho M, Shikanov A. Annals of Biomedical Engineering, 2017.

​https://www.ncbi.nlm.nih.gov/pubmed/28028710

2016

37. The artificial ovary: current status and future perspectives.

Amorim CA, Shikanov A. Future Oncology, 2016.

http://www.futuremedicine.com/doi/abs/10.2217/fon-2016-0202?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed


36. Synthetic hydrogel supports the function and regeneration of artificial ovarian tissue in mice. 

Kim J, Perez AS, Claflin J, David A, Zhou H, Shikanov A.

Regenerative Medicine, 2016. 

https://rdcu.be/bb5uT  http://www.nature.com/articles/npjregenmed201610

35. The Synergistic Effects of Matrix Stiffness and Composition on the Response of Chondropogenitor Cells in a 3D Precondensation Microenvironment.

Carrion B, Souzanchi MF, Wang VT, Tiruchinapally G, Shikanov A, Putnam AJ, Coleman RM.

Advanced Healthcare Materials, 2016.

http://www-ncbi-nlm-nih-gov.proxy.lib.umich.edu/pubmed/26959641

34. Immunoisolation to prevent graft rejection: current knowledge and future use,

David A, Day JR, Shikanov A.  

Experimental Biology and Medicine, 2016.

http://www-ncbi-nlm-nih-gov.proxy.lib.umich.edu/pubmed/27188513


33. In vitro culture methods of preantral follicles.

Green LJ, Shikanov A.  

The Theriogenology, 2016.

http://authors.elsevier.com/a/1T6KW,28LgsLNN

32. Characterization of the crosslinking kinetics of multi-arm poly(ethylene glycol) hydrogels formed via Michael-type addition.  

Kim J, Kong YP, Niedzielski SM, Singh RK, Putnam AJ, Shikanov A.  

Soft Matter, 2016.

http://www.ncbi.nlm.nih.gov/pubmed/?term=Characterization+of+the+crosslinking+kinetics+of+multi-arm+poly(ethylene+glycol)+hydrogels+formed+via+Michael-type+addition

2013-2015

31. Hydrogel Based 3-Dimensional (3D) System for Toxicity and High-Throughput (HTP) Analysis for Cultured Murine Ovarian Follicles.  

Zhou H, Malik MA, Arab A, Hill MT, Shikanov A.

PLoS One, 2015.

http://www.ncbi.nlm.nih.gov/pubmed/?term=Hydrogel+Based+3-Dimensional+(3D)+System+for+Toxicity+and+High-Throughput+(HTP)+Analysis+for+Cultured+Murine+Ovarian+Follicles

30. Characterizing natural hydrogel for reconstruction of three-dimensional lymphoid stromal network to model T-cell interactions.  

Kim J, Wu B, Niedzielski SM, Hill MT, Coleman RM, Ono A, Shikanov A.

J Biomed Mater Res A, 2015.

http://www.ncbi.nlm.nih.gov/pubmed/25649205

29. Bioengineering the Ovarian Follicle Microenvironment.

Shea LD, Woodruff TK, Shikanov A.  

Annu Rev Biomed Eng, 2013. 

       *The 2014 review “Bioengineering the Ovarian Follicle Microenvironment” was highlighted on the Global Medical Discovery webpage.

​http://www-ncbi-nlm-nih-gov.proxy.lib.umich.edu/pubmed/24849592

28. Simple multi-level microchannel fabrication by pseudo-grayscale backside diffused light lithography.  

Lai D, Labuz JM, Kim J, Luker GD, Shikanov A, Takayama S.

RSC Advances, 2013.

http://pubs.rsc.org/en/Content/ArticleLanding/2013/RA/c3ra43834a#!divAbstract

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PUBLICATIONS FROM SHEA LAB - 

27. Fibrin-mediated delivery of an ovarian follicle pool in a mouse model of infertility.

Smith RM*, Shikanov A*, Kniazeva E, Ramadurai D, Woodruff T, Shea LD.

Tissue Eng Part A, 2014.

http://www-ncbi-nlm-nih-gov.proxy.lib.umich.edu/pubmed/24802617

26. The impact of adhesion peptides within hydrogels on the phenotype and signaling of normal and cancerous mammary epithelial cells.

Weiss MS, Bernabé BP, Shikanov A, Bluver DA, Mui MD, Shin S, Broadbelt LJ, Shea LD.

Biomaterials, 2012. 

http://www.ncbi.nlm.nih.gov/pubmed/22341213

 

25. Hydrogel design for supporting neurite outgrowth and promoting gene delivery to maximize neurite extension.

Shepard JA, Stevans AC, Holland S, Wang CE, Shikanov A, Shea LD.

Biotechnol Bioeng, 2012. 

http://www.ncbi.nlm.nih.gov/pubmed/22038654

24. Fibrin Encapsulation and VEGF Delivery Promotes Ovarian Graft Survival in Mice, Shikanov A, Zhang J, Xu M, Smith RM, Rajan A, Woodruff TK, Shea LD,

Tissue Eng Part A, 2011.http://www.ncbi.nlm.nih.gov/pubmed/21740332http://www.ncbi.nlm.nih.gov/pubmed/21740332

 

23. Gene therapy vectors with enhanced transfection based on hydrogels modified with affinity peptides.

Shepard JA, Wesson PJ, Wang CE, Stevans AC, Holland SJ, Shikanov A, Grzybowski BA, Shea LD.

Biomaterials, 2011. 

http://www.ncbi.nlm.nih.gov/pubmed/21514659

​ 

22. A Method for Ovarian Follicle Encapsulation and Culture in a Proteolytically Degradable 3 Dimensional System,

Shikanov A, Xu M, Woodruff TK, Shea LD,

Journal of Visualized Experiments (JoVE), 2011. 

http://www.ncbi.nlm.nih.gov/pubmed/21445043

 

21. Hydrogel network design using multifunctional macromers to coordinate tissue maturation in ovarian follicle culture, 

Shikanov A*, Smith RM*, Xu M, Woodruff TK, Shea LD, (* equal contribution)

Biomaterials, 2011,

http://www.ncbi.nlm.nih.gov/pubmed/21247629

 

20. In vitro Oocyte Maturation and Preantral Follicle Culture from the Luteal Phase Baboon Ovary Produce Mature Oocyte,

Xu M, Fazleabas AT, Shikanov A, Jackson E, Barrett SL, Hirshefeld-Cytron J, Kiesewetter SE, Shea LD, Woodruff TK,

Biol Reprod, 2010. 

http://www.ncbi.nlm.nih.gov/pubmed/21123815

 

19. Balancing cell migration with matrix degradation enhances gene delivery to cells cultured three dimensionally within hydrogels,

Shepard JA, Huang A, Shikanov A, Shea LD.

J Control Release, 2010. 

http://www.ncbi.nlm.nih.gov/pubmed/20450944

18. A novel two-step strategy for in-vitro culture of early stage ovarian follicles in the mouse,

Jin SY, Lei L, Shikanov A, Shea LD, Woodruff TK.

Fertil Steril, 2010. 

http://www.ncbi.nlm.nih.gov/pubmed/20004373

 

17. Interpenetrating Fibrin-Alginate matrices for in vitro Ovarian Follicle Development, Shikanov A, Xu M, Woodruff TK, Shea LD.

Biomaterials, 2009. 

http://www.ncbi.nlm.nih.gov/pubmed/19616843

 

16. Fibrin hydrogels for non-viral vector delivery in vitro,

dex Rieux A, Shikanov A, Shea LD.

J Control Release, 2009. 

http://www.ncbi.nlm.nih.gov/pubmed/19232532

PUBLICATIONS FROM DOMB LAB

15. Cisplatin tumor biodistribution and efficacy after intratumoral injection of a biodegradable extended release implant,

Shikanov A, Shikanov S, Vaisman B, Golenser J, Domb AJ.

Chem Res Practice, 2011.

http://www.ncbi.nlm.nih.gov/pubmed/22295203

14. Poly(sebacic acid co-ricinoleic acid) biodegradable carrier for intratumoral delivery of paclitaxel, J Biomed Mater Res,

Shikanov A, Vaisman B, Shikanov S, Domb AJ.

Part A, 2010.

http://www.ncbi.nlm.nih.gov/pubmed/19343769

13.Local controlled delivery of anti-neoplastic RNAse to the brain

Slager J, Tyler B, Shikanov A, Domb AJ, Shogen K, Sidransky D, Brem H.

Pharm Res, 2009.

http://www.ncbi.nlm.nih.gov/pubmed/19415468

12. Intratumoral delivery of paclitaxel for treatment of orthotopic prostate cancer,

Shikanov S, Shikanov A, Gofrit O, Nyska A, Corn B, Domb AJ.

Pharm Sci, 2009.

http://www.ncbi.nlm.nih.gov/pubmed/18661540

11. Paclitaxel tumor biodistribution and efficacy after intratumoral injection of a biodegradable extended release implant,

Shikanov A, Shikanov S, Vaisman B, Golenser J, Domb AJ.

Int J Pharm, 2008.

http://www.ncbi.nlm.nih.gov/pubmed/18406086

10.The isolation of ricinoleic acid from castor oil by salt-solubility-based fractionation for the biopharmaceutical applications,

Vaisman B, Shikanov A, Domb AJ.

J Am Oil Chem Society, 2008.

9. Long acting local anesthetic-polymer formulation to prolong the effect of analgesia,

Shikanov A, Domb AJ, Weiniger CF.

J Control Release, 2007.

​http://www.ncbi.nlm.nih.gov/pubmed/18406086

8. Poly(sebacic acid-co-ricinoleic acid) biodegradable injectable in situ gelling polymer 

Shikanov A, Domb AJ.

Biomacromolecules, 2006.

http://www.ncbi.nlm.nih.gov/pubmed/16398527

7. Poly(sebacic acid-co-ricinoleic acid) biodegradable carrier for paclitaxel – effect of additives, Shikanov A, Ezra A, Domb AJ.

J Control Release, 2005.

http://www.ncbi.nlm.nih.gov/pubmed/15955366

6. Normal phase high performance liquid chromatography for determination of paclitaxel incorporated in a lipophilic polymer matrix

Vaisman B, Shikanov A, Domb AJ.

J Chrom A, 2005.

http://www.ncbi.nlm.nih.gov/pubmed/15729823

5. Biodegradable polymers: An update, 

Shikanov A, Kumar N, Domb, AJ.

Isr J Chemistry, 2005. Review.

 

4. Poly(sebacic acid-co-ricinoleic acid)biodegradable carrier for paclitaxel: In vitro release and in vivo toxicity, 

Shikanov A, Vaisman B, Krasko MY, Nyska A, Domb AJ,

Journal of Biomedical Materials Research Part A, 2004.

http://www.ncbi.nlm.nih.gov/pubmed/14999750

3. Intravenous and regional paclitaxel formulations

Pawar R, Shikanov A, Vaisman B, Domb AJ,

Curr Med Chem, 2004. Review.

http://www.ncbi.nlm.nih.gov/pubmed/14965220

2. Poly(ester anhydride)s prepared by the insertion of ricinoleic acid into poly(sebacic acid), 

Krasko MY, Shikanov A, Ezra A, Domb AJ,

J Polym Sci Part A – Polymer Chemistry, 2003.

1.Polylactones 57. Biodegradable networks based on A-B-A triblock segments containing poly(ethylene glycol)s-syntheses and drug release properties

Kricheldorf HR, Fechner B, Shikanov A, Domb AJ,

Biomacromolecules, 2003.

http://www.ncbi.nlm.nih.gov/pubmed/12857078

Pub Med

 

Dr. Ariella Shikanov speaks at the 2019 Oncofertility Conference about new models of Ovarian Regeneration.

University of Michigan's Ariella Shikanov describes her focus in developing functional and tunable hydrogels for reproductive tissue engineering. Presented on March 27, 2017.